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Correlated Genos/Phenos Subsets.

TiPRanavir / TPR / P overview.

Remark: Some data relate to Subset#1 (Free) used as an example (1 out of 25). You can access an INFO file with Raw data to analyse and complete the picture. Click HERE.

If you want to catch  the Subset#1  Dataset (or even more) Click HERE. 

I. G/Ps Content and Clades Prevalance.

II. Drug Resistance accross G/Ps.

NGYX I.C. Comment(s):  "Probably" the most interesting drug of the 22 FDA approved ones. OK there are definitively too much Phenotypic values under the Test Dynamic Range lower Limit. But the profile suggests that there is almost no resistance to TPR phenotypically. BUT...Here it would have been interesting to add to add 2-3 measurements / dilutions Sensitive side to confirm this first assumption.

III. Additional Remarks.

A. TPV is rated at 85% on the NGYX I.C.Scale of Drug Resistance Interest (DRI). This means that each couple of G/P is valuable maximally for 0.85 Euros. If you want to know more about DRI Click HERE.

B. Combining subsets will impact the number of variables (mutations / clades) that NGIX I.C. classify as "ACCEPTED". T0 know more about this Click HERE.