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Correlated Genos/Phenos Subsets.

STaVudine / STV / R overview.

Remark: Some data relate to Subset#1 (Free) used as an example (1 out of 25). You can access an INFO file with Raw data to analyse and complete the picture. Click HERE.

If you want to catch the Subset#1  Dataset (or even more) Click HERE. 

I. G/Ps Content and Clades Prevalance.

II. Drug Resistance accross G/Ps.

NGYX I.C. Comment(s): A Phenotypic results distribution (various sources) that not only shows numerous values under the test dynamic lower limit but also highlights the point that Drug Dilutions to generate IC50 values were to distant = often x4/x5. Switch to x2/x3 and adding 2-3 measurements would have been very beneficial to optimize sensitivity of the test (together with a shift on the sensitive side).

III. Additional Remarks.

A. STV is rated at 35% on the NGYX I.C.Scale of Drug Resistance Interest (DRI). This means that each couple of G/P is valuable maximally for 0.35 Euros. If you want to know more about DRI Click HERE.

B. Combining subsets will impact the number of variables (mutations / clades) that NGIX I.C. classify as "ACCEPTED". T0 know more about this Click HERE.