II. Drug Resistance accross G/Ps.
NGYX I.C. Comment(s): Similarly to TNF Phenotypic results (various sources) almost perfectly fall within the test dynmic range (a little bit to much values Under the test lower Dynamic range limit) . But here also the point is that (and this appears for many drugs) Drug Dilutions to generate IC50 values were to distant = often x4/x5. Switch to x2/x3 and adding 2-3 measurements would have been very beneficial to optimize sensitivity of the test.
III. Additional Remarks.
A. ABC is rated at 40% on the NGYX I.C.Scale of Drug Resistance Interest (DRI). This means that each couple of G/P is valuable maximally for 0.40 Euros. If you want to know more about DRI Click HERE.
B. Combining subsets will impact the number of variables (mutations / clades) that NGIX I.C. classify as "ACCEPTED". T0 know more about this Click HERE.